1. Differentiation and molecular characterization of endothelial progenitor and vascular smooth muscle cells from induced pluripotent stem cells

Mohammadreza Dastouri* , Hilal Ozdag , Ahmet Ruchan Akar , Alp Can

Bioimpacts. 2023;13(4): 289-300. doi: 10.34172/bi.2022.24132

PMCID: PMC10460769 PMID: 37645025 Scopus ID: 85168143106

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In this study, we demonstrate a multi-step differential differentiation of iPS cells into EPCs and VSMCs, unlike previous studies in which iPS cells have been induced to differentiate into ECs. Concomitantly, during the differentiation protocol, Myc and Klf4 oncogene expressions were also analyzed from a translational perspective.

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